Stop genetic illness with preimplantation genetic testing for monogenic disease, or PGT-M
Through preimplantation genetic testing for monogenic or disease, or PGT-M, we can reduce the likelihood that a baby will have a known genetic disorder. It uses in vitro fertilization (IVF) to create embryos which a lab then screens for specific genetic mutations. At Fertility Specialists of Texas, our team can handle the complex and difficult cases involving PGT-M.
About preimplantation genetic testing for monogenic
When a couple has a genetic defect in their family history, they may seek PGT-M to increase the chance of having a healthy baby. After retrieving the eggs from the ovary, our laboratory fertilizes them to form embryos. Our team then performs a biopsy to remove 5-7 cells from the embryos. A lab analyzes the gene that carries the disease for the presence of the disease-causing mutation. We can then transfer those embryos that show normal biopsy results.
Through state-of-the-art PGT-M techniques, our physicians and staff can screen for a wide variety of diseases. These include cystic fibrosis, sickle cell disease, Huntington’s disease and other genetic conditions. When a genetic disease is part of a family’s history, preimplantation genetic testing for monogenic offers new hope.
Limitations of PGT-M
PGT-M testing cannot screen for all genetic diseases. Additionally, it cannot determine the absence of a genetic condition with 100% certainty. During your consultation, our team will help you fully understand all aspects of treatment.
PGT-M can screen for the following conditons.
- Adenosine Deaminase Deficiency
- Alpha-1-Antitrypsin Deficiency
- Alzheimer’s disease (AAP gene)
- Cystic fibrosis
- Epidermolysis Bullosa
- Fanconi anemia
- Gaucher’s disease
- Hemophilia A and B
- Huntington’s disease
- Muscular dystrophy (Duchenne and Becker)
- Myotonic dystrophy
- Neurofibromatosis Type 1
- OTC deficiency
- P53 cancers
- Retinitis Pigmentosa
- Sickle cell disease
- Spinal muscular atrophy
- Tay Sachs disease
- Any genetically abnormal embryos (Trisomy 21, 13)
For PGT-M, we use: CooperGenomics NJ:
3 Regent Street, Suite 301
Livingston, NJ 07039