Fertility Specialists of Texas

Preimplantation Genetic Testing (PGT-M)

Stop genetic illness with preimplantation genetic testing for monogenic disease, or PGT-M

Through preimplantation genetic testing for monogenic or disease, or PGT-M, we can reduce the likelihood that a baby will have a known genetic disorder. It uses in vitro fertilization (IVF) to create embryos which a lab then screens for specific genetic mutations. At Fertility Specialists of Texas, our team can handle the complex and difficult cases involving PGT-M.

About preimplantation genetic testing for monogenic

When a couple has a genetic defect in their family history, they may seek PGT-M to increase the chance of having a healthy baby. After retrieving the eggs from the ovary, our laboratory fertilizes them to form embryos. Our team then performs a biopsy to remove 5-7 cells from the embryos. A lab analyzes the gene that carries the disease for the presence of the disease-causing mutation. We can then transfer those embryos that show normal biopsy results.

Through state-of-the-art PGT-M techniques, our physicians and staff can screen for a wide variety of diseases. These include cystic fibrosis, sickle cell disease, Huntington’s disease and other genetic conditions. When a genetic disease is part of a family’s history, preimplantation genetic testing for monogenic offers new hope.

Limitations of PGT-M

PGT-M testing cannot screen for all genetic diseases. Additionally, it cannot determine the absence of a genetic condition with 100% certainty. During your consultation, our team will help you fully understand all aspects of treatment.

PGT-M can screen for the following conditons.

  • Achondroplasia
  • Adenosine Deaminase Deficiency
  • Alpha-1-Antitrypsin Deficiency
  • Alzheimer’s disease (AAP gene)
  • Betathalasemia
  • Cystic fibrosis
  • Epidermolysis Bullosa
  • Fanconi anemia
  • Gaucher’s disease
  • Hemophilia A and B
  • Huntington’s disease
  • Muscular dystrophy (Duchenne and Becker)
  • Myotonic dystrophy
  • Neurofibromatosis Type 1
  • OTC deficiency
  • P53 cancers
  • Phenylketonuria
  • Retinitis Pigmentosa
  • Sickle cell disease
  • Spinal muscular atrophy
  • Tay Sachs disease
  • Any genetically abnormal embryos (Trisomy 21, 13)

For PGT-M, we use: CooperGenomics NJ:
3 Regent Street, Suite 301
Livingston, NJ 07039
Phone: 1-877-282-3112